Effect of blood pressure variability on new-onset atrial fibrillation in elderly patients with essential hypertension
Abstract：Objective To study the effect of blood pressure variability on new-onset atrial fibrillation (AF) in elderly patients with essential hypertension.Methods Six hundred and eighty-three elderly patients with essential hypertension admitted to our hospital from January 2010 to December 2011 were divided into AF group (n=69) and AF-free group (n=614).Their baseline characteristics,echocardiographic parameters and ambulatory blood pressure were recorded.The patients were further divided into high variability group (n=342) and low variability group (n=341) according to their median SBP variability (9.89 mm Hg).The effect of blood pressure variability on new-onset AF was analyzed by multivariate Cox regression analysis.Results The 24 h SBP variability was significantly higher whereas the 24 h DBP was significantly lower in AF group than in AF-free group (11.13±3.50 mm Hg vs 10.21±3.41 mm Hg,P=0.034;67.19±8.16 mm Hg vs 69.33±8.39 mm Hg,P=0.045).Multivariate Cox regression analysis showed that the 24 h SBP variability,cerebral hemorrhage,and cardiac pacemaker implantation were independent risk factors for new-onset AF (P＜0.05,P＜0.01).Conclusion The 24 h SBP variability is an independent risk factor for new-onset AF in elderly patients with essential hypertension.
Keywords：hypertensionatrial fibrillationechocardiographyblood pressure monitoringambulatoryrisk factors
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 228-231 )