Relation between mild anemia and orthostatic hypotension in elderly multimorbidity patients
Abstract：Objective To study the relation between mild anemia and OH by investigating the incidence of OH in elderly patients with multimorbidity and polypharmacy.Methods One hundred and two patients with multimorbidity and polypharmacy were divided into 60-79 years old group (n=56) and≥80 years old group (n=46).Their supine and orthostatic blood pressures were measured.The incidence of OH,blood biochemical parameters and general clinical data were analyzed.Results The percentage of males was higher,the age was older,the incidence of OH,mild anemia,CHD,stroke,the serum Cr and Cys-C levels were significantly higher while the BMI,Hb,HCT,FPG,albumin and eGFR were significantly lower in ≥80 years old group than in 60-79 years old group (P＜0.05,P＜0.01).Mild anemia was positively related with OH in elderly patients (OR =4.760,95 ％ CI:1.569-14.444,P =0.006) even after adjustment for age,BMI,albumin,prealbumin,TG,TC,HDL-C,Cys-C (OR=4.977,95％CI:1.111-22.309,P=0.036).Conclusion The incidence of OH and mild anemia is closely related with age,especially in advance-aged patients.Mild anemia is an independent risk factor for OH in elderly patients with multimorbidity and polypharmacy,anemia screening and intervention should thus be strengthened.
Keywords：anemiahypotensionorthostaticdrug interactionsrisk factors
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 163-166 )