Change of cerebral perfusion parameters in patients with middle cerebral artery stenosis during a short-term follow-up time
Abstract：Objective To observe the change of cereberal perfusion parameters in patients with unilateral middle cerebral artery stenosis during a short-term follow-up time.Methods Nineteen of the 35 patients with unilateral middle cerebral artery stenosis who underwent CTP were followed up and divided into moderate stenosis (50％-69％) group (n=10) and severe stenosis (70％-99％) group (n=9) according to their middle cerebral artery stenosis.Their cerebral blood flow (CBF),cerebral volume (CBV),mean transit time (MTT) and time to peak (TTP) were recorded in the interested regions of basal ganglia,corona radiate and centrum semiovale and compared with rCBF,rCBV,rMTT and rTTP in the normal side.The cerebral perfusion parameters before and 3 months after CTP were compared.Results Of the 19 patients with unilateral middle cerebral artery stenosis,7 (36.8％) had improvement in their CTP parameters,7 (36.8％) had no improvement in their CTP parameters,5 (26.3％) were deteriorated in their CTP parameters.The rTTP was longer in 5 pateints and the rCBF was slower in 4 patients.Improvement,no improvement and deterioration were found in 6,3,1 patients of moderate stenosis group and in 1,4,4 patients of severe stenosis group.The rate of improvement was significantly higher in moderate stenosis group than in severe stenosis group (60.0％ vs 11.1％,P =0.040).Conclusion CTP parameters will change in patients with symptomatic unilateral symptomatic middle cerebral artery stenosis and improve in some of them during the short-term follow-up time.
Keywords：middle cerebral arteryperfusionregionalhemodynamicstomographyX-ray computedstenosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 121-125 )