Efficiency of CT perfusion imaging-guided thrombolytic therapy for acute ischemic stroke with unclear onset time
Abstract：Objective To study the efficiency and satety of CT perfusion (CTP)-guided thrombolytic therapy for acute ischemic stroke (AIS) with unclear onset time.Methods Sixty-one AIS patients with unclear onset time who underwent CTP were divided into CTP group (n=8),nonthrombolysis group (n =36),and control group (n =17).Their therapeutic effect,clinical curative rate and incidence of hemorrhage were assessed according to the NIHSS before and 24 h and 14d after treatment.Results No significant difference was found in the NIHSS scores between the three groups before treatment (P＞0.05).The NIHSS score was significantly lower in CTP group and control group than in non-thrombolysis group 24 h and 14 d after treatment (P＜0.01).No significant difference was found in the NIHSS score between CTP group and control group (P＞0.05).The curative rate was significantly higher in CTP group and control group than in nonthrombolysis group (62.5％00 vs 11.1％,58.8％ vs 11.1％0,P=0.006,P=0.001).No significant difference was found in the curative rate between CTP group and control group (P =1.000).Conclusion CTP is of certain guiding significance in intraveinous therapy for AIS with uncertain onset time.
Keywords：brain infarctiontissue plasminogen activatortomographyX-ray computedintracranial hemorrhages
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 47-50 )