Effect of hyperhomocysteinemia on arterial stiffness in elderly essential hypertension patients
Abstract：Objective To study the effect of hyperhomocysteinemia (HHcy) on arterial stiffness in elderly essential hypertension patients.Methods Sixty-six elderly essential hypertension patients served as a hypertension group and 58 elderly subjects without hypertension history served as a control group in this study.Their serum levels of blood lipid,fasting blood glucose,insulin,Hcy,and HOMA-IR index were measured and their arterial stiffness was assessed according to their cfPWV.Results The Hcy level and cfPWV were significantly higher in hypertension group than in control group (P＜0.05).The Hcy level was positively related with the cfPWV (r=0.529,95％CI:0.040-0.079,P＜0.01).The HOMA-IR index and cfPWV were significantly higher in hypertension group than in control group (P＜0.01).Conclusion Elevated arterial stiffness is related with insulin resistance in elderly essential hypertension patients with HHcy.
Keywords：hyperhomocysteinemiahypertensionarteriosclerosisinsulin resistance
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 28-30 )