Effect of serum uric acid level on coronary artery instent restenosis
Abstract：Objective To study the effect of serum uric acid (UA ) level on coronary artery instent restenosis in patients with SAP .Methods One hundred and thirty‐six SAP patients 12 -18 months after stenting were divided into restenosis group (n=62) with their restenosis ≥50% and control group (n=74)with their restenosis <50% .Results The serum UA level was significant‐ly lower in control group than in restenosis group (364 .21 ± 42 .47 μmol/L vs 440 .66 ± 69 .05μmol/L ,P=0 .000) .The MLD was significantly longer ,the incidence of stenosis was significantly lower ,and the advanced lumen diameter was significantly shorter in control group than in resteno‐sis group 12-18 momths after stgenting (2 .12 ± 0 .38 mm vs 0 .76 ± 0 .37 mm ,P= 0 .013 ;35.84% ±12.34% vs84.53% ±14.26% ,P= 0.000;0.27±0.14mm vs1.66±0.57mm,P=0.000) .Multivariate logistic regression analysis showed that serum UA level was associated with restenosis after stenting (OR=0 .680 ,95% CI:0 .564-0.937 ,P<0 .05) .Conclusion Elevated se‐rum UA level is one of the mechanisms for restenosis in SAP patients after stenting .
Keywords：uric acidangina pectorisstentscoronary angiographycoronary restenosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1160-1162 )