Relationship between epicardial adipose tissue thickness measured by transthoracic echocardiography and CHD in the elderly
Abstract：Objective To evaluate the relationship between epicardial adipose tissue (EAT ) thick‐ness measured by transthoracic echocardiography (TTE) and CHD in the elderly .Methods Sev‐enty‐seven patients with their age ≥60 years were divided into CHD group (n=57)and non‐CHD group (n=20)according to their coronary arterioangiography .Their EAT thickness was measured by TTE .The clinical data and EAT thickness were compared between the two groups .The rela‐tionship between EAT thickness and CHD was analyzed using logistic regression model and ROC curve .Results The EAT thickness was significantly thicker in CHD group than in non‐CHD group (5 .26 ± 1 .77 mm vs 3 .60 ± 1 .03 mm ,P=0 .000) .The ratio of EAT thickness ≥4 .14 mm was significantly higher in CHD group than in non‐CHD group(71 .9% vs 25 .0% ,P=0 .000) . Logistic regression analysis showed that the EAT thickness was an independent risk factor for CHD (OR=6 .009 ,95% CI:1 .436 -25 .148 ,P=0 .014) .The sensitivity and specificity of EAT thickness ≥ 4 .14 mm were 71 .9% and 75 .0% for the diagnosis of CHD ,the area under ROC curve was 0 .783 (95% CI:0 .678 -0 .898 ,P<0 .01) .Conclusion The EAT thickness measured by TTE is closely related with CHD in the elderly with their age ≥60 years and can thus be used as an effective non‐invasive method in diagnosis of CHD in the elderly .
Keywords：echocardiographycoronary diseasecoronary angiographyROC curveC-reactive pro-tein
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 949-952 )