Effect of anemia on clinical outcomes in patients with heart failure with preserved ejection fraction
Abstract：Objective To assess the effect of anemia on clinical outcomes in patients with heart fail‐ure with preserved ejection fraction (HFPEF) by studying the clinical features of HFPEF .Meth‐ods Three hundred and twenty‐five HFPEF patients admitted to our hospital were divided into anemia group (n= 84) and non‐anemia group (n= 241) .Their clinical and laboratory data were collected .The patients were followed up for 9 -26 (17 .5 ± 8 .3) months .The risk factors for HFPEF were analyzed using Kaplan‐Meier survival curve and Cox proportional hazard regression model .Results The all‐cause death rate or end point events during rehospitalization due to HF was significantly higher in anemia group than in non‐anemia group (67 .9% vs 48 .1% ,P=0.002) .Anemia ,NYHA grade and chronic renal insufficiency were the independent risk factors for HFPEF ,and anemia was the most powerful influence factor (OR= 5 .012 ,95% CI:3 .271 -6.160 ,P=0 .006) .Conclusion Anemia is an independent risk factor for HFPEF ,and more atten‐tion should thus be paid to anemia in diagnosis and treatment of HFPEF .
Keywords：anemiastroke volumeheart failurerenal insufficiencyprognosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 942-944 )