High-resolution MRI of carotid atherosclerotic plaques in diabetes mellitus patients
Abstract：Objective To study the carotid atherosclerotic plaques in diabetes mellitus (DM ) pa‐tients and normal glycometabolism subjects .Methods Thirty DM patients served as a DM group and 28 normal glycometabolism subjects served as a non‐DM group in this study .Their carotid plaque compositions and carotid artery morphology were analyzed by scanning the carotid artery with high‐resolution 3 .0T MR .Results Atherosclerotic plaques were formed in 49 branches of coronary artery in DM group and 47 ranches of coronary artery in non‐DM group .The incidence of calcified plaques and thin/ruptured fibrous caps was significantly higher in DM group than in non‐DM group (83 .67% vs 55 .32% ,P= 0 .002;67 .35% vs 42 .55% ,P= 0 .015) .The incidence of plaque bleeding was significantly lower in DM group than in non‐DM group (36 .73% vs 44 .68% , P=0 .428) .No significant difference was found in IPH and LRNC between the two groups (P=0 .523) .The maximum thickness of plaques was greater in DM group than in non‐DM group (4 .31 ± 1 .59 mm vs 4 .01 ± 1 .62 mm ,P=0 .017) .No significant difference was found in total vas‐cular area and vascular wall standard index between DM group non‐DM group (72 .55 ± 30 .17 mm2 vs 81 .54 ± 34 .15 mm2 ,P=0 .432 ;0 .72 ± 0 .13 vs 0 .66 ± 0 .15 ,P=0 .255) .Conclusion The stability of carotid atherosclerotic plaques is lower in DM patients than in normal glycometabolism subjects .
Keywords：diabetes mellituscarotid artery diseasesatherosclerosismagnetic resonance imagingrisk factors
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 907-910 )