Identification and treatment of agitation symptoms in dementia patients
Abstract：Objective To study the therapeutic effect of memantine on agitation symptoms by early identifying them in dementia patients .Methods Neuropsychology was assessed in 10 dementia patients with behavioral and psychological symptoms according to MMSE ,MoCA and NPI .The patients underwent brain MRI and PIB‐PET MRI scanning for further diagnosis of agitation symptoms and reexamined 3 months after they were treated with memantine .Results The agi‐tated ,aggressive ,irritative and anxiety symptoms were siginificantly improved in all the 10 pa‐tients ,and their cognitive function and daily living ability were also improved .The typical symp‐toms in 3 out of the 10 dementia patients were significantly improved .The mild agitation symp‐toms that were difficult to identify could be effectively treated with memantine .Conclusion The early the agitation symptoms are diagnosed ,the better the therapeutic effect is .
Keywords：dementianeuropsychological testsirritable moodcognition disordersmemantine
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 250-252 )