Effect of blood pressure variability during follow-up on recurrent ischemic stroke
Abstract：Objective To study the effect of blood pressure (BP) variability during follow-up on re-current ischemic stroke .Methods T he BP of 698 patients undergoing cilostazol and aspirin treat-ment in 12 hospitals for prevention of recurrent ischemic stroke was retrospectively analyzed .The hazard ratio ( H R) for the effect of BP variability during follow-up on recurrent ischemic stroke was calculated according to the Cox proportion risk regression model .Results The SD of SBP and the HR of BP variability were related with the mean SBP during follow-up (r=0 .282 ,P=0.000;r=0 .128 ,P=0 .001) .After adjustment for the mean SBP ,the HR was 3 .641 (95% CI:2.368-5 .599) for the SD of SBP ,3 .327 (95% CI:2 .130 -5 .195) for the variability of SBP , 3.657 (95% CI:2 .320 -5 .763) for the VIM of SBP ,and 4 .149 (95% CI:2 .381 -7 .229) for the mean value of DBP (P=0 .000) .No significant difference was found in the SD ,HR ,and VIM of DBP (P> 0 .05) .After adjustment for the mean pulse pressure ,the HR was 4 .973 (95% CI:3 .295-7.506) for the SD of pulse pressure and 6 .410 (95% CI:3 .898-10 .538)for the variabili-ty of pulse pressure ( P=0 .000 ) .Conclusion T he variability of SBP and pulse pressure during follow-up is a risk factor for recurrent ischemic stroke .However ,the variability of DBP is not a risk factor for recurrent ischemic stroke .
Keywords：blood pressure determinationstrokerecurrenceischemic attacktransientatheroscle-rosis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1065-1068 )