Relation between intracranial atherosclerotic stenosis and acute ischemic stroke progression
Abstract：Objective To study the relation between intracranial atherosclerotic stenosis and acute ischemic stroke (AIS) progression .Methods Two hundred and seventy-two AIS patients admit-ted to our hospital from January 2011 and January 2014 were divided into progressive neurological dysfunction (PND) group (n=64) and non-PND group (n=208) .Cerebral atherosclerotic lesions were divided into intracranial circulation system lesion ,extracranial circulation system lesion ,an-terior circulation system lesion ,and posterior circulation system lesion according to their angio-graphic findings .Incidence of atherosclerotic stenosis in different circulation systems was com-pared .Results The proportion of female patients ,lesion size≥15 mm ,intracranial atherosclerotic stenosis ,and extracranial atherosclerotic stenosis was significantly higher in PND group than in non-PND group (45 .3% vs 31 .7% ,P=0 .046 ;42 .2% vs 28 .8% ,P=0 .045;45 .3% vs 29 .8% , P=0 .022 ;53 .1% vs 38 .0% ,P=0 .032) .The NIHSS scale was significantly higher in PND group than in non-PND group[7(4 ,9) vs 6(3 ,8) ,P=0 .033] .Logistic regression analysis showed that intracranial atherosclerotic stenosis was an independent risk factor for PND (OR=1 .961 ,95% CI:1 .070-3.592 ,P=0 .029) .Conclusion Intracranial atherosclerotic stenosis is an independent risk factor for early PND in AIS patients .
Keywords：intracranial arteriosclerosisbrain infarctionatherosclerosisembolushemodynamicrisk factors
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1061-1064 )