Curative effect of modified cocktail therapy on multiple system atrophy
Abstract：Objective To study the curative effect of modified cocktail therapy on multiple system atrophy (MSA) .Methods Nine MSA patients who were treated with modified cocktail therapy followed by Dl-3n butyphthalide for 2-3 weeks .The curative effect of modified cocktail therapy and Dl-3n butyphthalide on MSA was assessed at admission ,6 months and 1 year after treatment according to the MSA Assessment Scale .Results The patients were followed up for 6 months and 1 year .The language score was significantly lower at 6 months and 1 year of follow-up than at admission (1 .55 ± 0 .52 vs 2 .44 ± 0 .72 ,1 .66 ± 0 .86 vs 2 .44 ± 0 .72 ,P=0 .030) .However ,no sig-nificant difference was found in the language score at 6 months and 1 year of follow-up ( P>0.05) .The scores of walking ,falling ,lower limb movement flexibility and standing from seat were significantly higher at 6 months of follow-up than at adimission (P<0 .05 ,P<0 .01) .However , no significant difference was found in the scores at 1 year of follow-up and at admission (P>0.05) .Conclusion Modified cocktail therapy is of certain curative effect on some symptoms of M SA patients .
Keywords：multiple system atrophythiamineriboflavinVitamin EVitamin K3folic acid
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 958-960 )