Nonmotor syndrome in multiple system atrophy
Abstract：Objective To summarize the constitutional ratio of multiple system atrophy (MSA)ini-tially manifested as nonmotor or motor syndrome .Methods Thirty-one MSA patients were divid-ed into MSA-P type group (n=18) and MSA-C type group (n=13) .Their medical history ,mani-festations and their development time of motor or nonmotor symdrome were recorded .Results MSA was initially manifested as nonmotor syndrome in 23 MSA patients .Its common initial symptoms were rapid eyemovement sleep behavior disorder ,urinary dysfunction ,sexual disorder , and orthostatic hypotension .MSA was initially manifested as motor syndrome in 31 MSA pa-tients .Its common initial symptoms were rectal dysfunction ,urinary dysfunction ,orthostatic hy-potension ,sleep apnea and rapid eyemovement sleep behaviour disorder ,accounting for 93 .5% , 90 .3% ,64 .5% ,61 .3% ,and 48 .4% respectively of its total symptoms .No significant difference was found in nonmotor syndrome and its morbidity between MSA-P type group and MSA-C type group (P>0 .05) .Conclusion MSA patients are usually manifested as nonmotor syndrome such as autonomic nervous dysfunction .Nonmotor syndrome is more commonly observed in MSA-C type patients than in MSA-P type patients .
Keywords：multiple system atrophyREM sleep behavior disordermovement disordersurination disorderssleep apnea syndromes
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 946-950 )