Relation between serum procalcitonin level and outcome in elderly patients with acute myocardial infarction
Abstract：Objective To study the relation between serum procalcitonin (PCT ) level and short-term clinical outcome in elderly patients with acute myocardial infarction (AMI) .Methods Nine-ty-seven elderly AMI patients served as an AMI group and 80 subjects undergoing physical exami-nation served as a control group in this study .Their serum PCT and hs-CRP levels were meas-ured .The patients were further divided into normal group with its serum PCT <0 .5 μg/L (n=23) ,mild group with its serum PCT 0 .5 -1 .9 μg/L (n=41) ,and severe group with its serum PCT ≥2 .0 μg/L(n=33) .The mortality and incidence of major adverse cardiac events (MACE)on day 30 of follow-up were recorded .Results The serum PCT and hs-CRP levels were significantly higher in AMI group than in control group (3 .14 ± 1 .59μg/L vs 0 .15 ± 0 .04μg/L ,95 .21 ± 20 .17 mg/L vs 11 .32 ± 9 .30 mg/L ,P<0 .01) .The mortality and incidence of MACE were significantly higher in normal group than in mild group (0% and 7 .3% vs 24.2% ,13 .0% and 22 .0% vs 45.5% ,P<0 .05) .The serum PCT level was positively related with the serum hs-CRP level (r=0 .4721 ,P=0 .032) .The serum PCT level could predict the mortality and incidence of MACE on day 30 of follow-up (OR=5 .011 ,4 .312 ,P<0 .01) .Conclusion The serum PCT level is higher in elderly AMI patients and can predict their short-term(within 30 days)outcome and MACE .
Keywords：myocardial infarctionprocalcitoninC-reactive proteininflammationprognosis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 916-919 )