Assessment of quality of life of patients with Parkinson's disease with questionnaire and analysis of its influencing factors
Abstract：Objective To assess the quality of life of patients with Parkinson's disease (PD) with EQ-5D questionnaire and analyze its influencing factors .Methods Fifty-two PD patients were in-cluded in this study .Their quality of life and health status were assessed according to the EQ-5D , UPDRS ,Hoehn-Yahr (H-Y ) stage ,PD sleep scale (PDSS ) ,Hamilton anxiety rating scale (HAMA)amd Hamilton depression rating scale (HAMD) .Results Insomnia (r= -0 .519) , UPDRS Ⅰ - Ⅳ (r= -0 .568 ,r= -0 .705 ,r= -0 .760 ,r= -0 .571) ,HAMD (r= -0 .669) , HAMA (r= -0 .549) ,H-Y stage (r= -0 .694) ,PDSS(r=1 .000) ,disease course (r= -0 .640) and education level (r=0 .293) were related with the quality of life of PD patients ( P<0 .01) . Multivariate regression analysis showed that the factors that influenced the EQ-5D index of PD patients were UPDRS Ⅰ ,UPDRS Ⅲ ,HAMD and PDSS .The UPDRS Ⅰ ,UPDRS Ⅲ ,HAMA and HAMD were negatively related with the EQ-5D index (P<0 .05 ,P<0 .01) ,while the PDSS was positively related with EQ-5D index (P<0 .01) .Conclusion EQ-5D can used in assessment of the quality of life of PD patients .Clinicians should pay their attention not only to the diagnosis of PD patients and treatment of their motor symptoms ,but also to their non-motor symptoms such as sleep ,anxiety and depression in order to improve their quality of life .
Keywords：Parkinson diseasequality of lifehealth statussleepanxiety
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 899-902 )