Association between HBV infection and symptomatic intracranial atherosclerotic stenosis
Abstract：Objective To study the association between HBV infection and symptomatic intracrani-al atherosclerotic stenosis .Methods One hundred and fifty-two patients with symptomatic in-tracranial atherosclerotic stenosis served as a stenosis group and 152 patients without symptomat-ic intracranial atherosclerotic stenosis served as a control group in this study .Their HBV serum antigens (HBsAg ,HBeAg) and antibodies (HBsAb ,HBcAb ,HBeAb) were detected by ELISA . The risk factors for intracranial atherosclerotic stenosis and the relation between HBV infection and intracranial atherosclerosis were analyzed .Results The age was older ,the incidence of hyper-tension and transient cerebral ischemia or ischemic stroke and the serum HbA 1c level were signif-icantly higher in stenosis group than in control group (P<0 .05) .The seroprevalence of HBV in-fection was significantly higher in stenosis group than in control group (40 .1% vs 18 .4% ,P<0.01) .Multivariate logistic regression analysis showed that HBV infection was an independent risk factor for intracranial atherosclerotic stenosis (OR= 2 .261 ,95% CI:1 .149 -4 .448 ,P<0.05) .Conclusion HBV infection is an independent risk factor for intracranial atherosclerotic stenosis .Its active intervention helps to prevent intracranial atherosclerotic stenosis .
Keywords：hepatitis B virusatherosclerosisintracranial arteriosclerosisstrokerisk factors
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 620-623 )