Relation between ambulatory blood pressure and arterial stiffness in the very elderly
Abstract：Objective To investigate the relation between ambulatory blood pressure and arterial stiffness in the very elderly. Methods 238 very elderly (age≥80 years) were divided into two groups: 104 normotensive and 134 hypertensive (BP≥160/95 mm Hg, 1 mm Hg=0.133 kPa).Ambulatory blood pressure and brachial-ankle pulse wave velocity(baPWV) were monitored for all subjects. The relationship between parameters of ambulatory blood pressure and arterial stiff-ness was analyzed by Pearson correlation. Results The baPWV of the hypertensive group was significantly higher than that of normotensive group (P < 0.05,P < 0. 01). The casual systolic blood pressure(SBP), 24 h, day(D) and night(N) SBP, diastolic blood pressure(DBP), pulse pres-sure(PP),SBP load and DBP load in hypertensive group were significantly higher than those in the normotensive group. The rates of nocturnal SBP decrease and DBP decrease in the hyperten-sive group were significantly lower than those in the normotensives (P < 0.05, P < 0.01). Pear-son correlation analysis showed that baPWV was positively correlated with casual SBP,casual DBP, 24 h SBP, DBP, PP; day SBP, DBP, PP, HR; night SBP, DBP, PP, SBP load and DBP load,negatively correlated with night SBP decrease (P<0.01). Conclusion Present findings suggest that increase in arterial stiffness is an important factor of hypertension in the very elderly. Arterial stiffness is correlated with ambulatory SBP,DBP,PP, HR and BP load.
Keywords：hypertensionarteriosclerosisblood pressure monitoringambulatoryheart rateage factors
Publication Date：2009-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 581-583 )