Research on the therapeutic effect of customized adjustable anti-snoring devices for orthodontics on obstructive sleep apnea-hypopnea syndrome
GAO Yuan
JIA Jingchen
LÜ Jing
CAI Chengxiong
LI Ying
DENG Tianzheng
Abstract：Objective To evaluate the clinical value of a personalized adjustable mandibular advancement device(MAD)in elderly patients with obstructive sleep apnea-hypopnea syndrome(OSAHS).Methods Sixty elderly OSAHS patients who attended the Department of Stomatology,Air Force Medical Center between May 2023 and November 2024 were enrolled and randomly divided into a control group and an experimental group,with 30 cases in each group.The control group received a conventional MAD,whereas the trial group received a customized adjustable MAD.Data on the lowest oxygen saturation(LSaO2),the proportion of time with blood oxygen saturation<90%(T90%),apnea index(AI),apnea hypopnea index(AHI),Epworth sleepiness scale(ESS),and Quebec sleep questionnaire(QSQ)were collected before and after treatment for both groups.The therapeutic effects and adverse reactions were also recorded.Results After treatment,both groups exhibited higher LSaO2 and QSQ scores and lower T90%,AI,AHI,and ESS scores than at baseline(P<0.05).Moreover,the trial group showed significantly greater improvements in LSaO2 and QSQ and larger reductions in T90%,AI,AHI,and ESS compared with the control group(P<0.05).The overall effective rate in the trial group was higher than that in the control group(90.00%vs 63.33%,P=0.015).No significant inter-group difference was observed in the overall incidence of adverse events(P>0.05).Conclusion The customized adjustable MAD markedly ameliorates nocturnal hypoxia and respiratory events,relieves daytime sleepiness,and improves quality of life in OSAHS patients,offering reliable efficacy with acceptable safety.
Keywords：obstructive sleep apnea syndromesnore guardsleep qualityblood oxygen saturationinflammatory factors
Publication Date：2025-11-20
Online Publishing Date：2025-12-02(First online date of this platform, not the publication date of the document)
Pages：5( 413-417 )