A preliminary study on the effect of DCEF on osseointegration of titanium implants

HAN Wei; GAO Yu-xuan; WANG Xiao-yu; LIU Na; LI Hong-bo

doi:10.3969/j.issn.1672-2973.2017.03.011

Abstract：Objective:To investigate the effect of direct current electric field (DCEF) on the osteointegration of titanium implants.Methods:Put the implants into the rat tibias.After 4 or 8 weeks of DCEF loading,the bone mineral density,implants rotation torque values and hard tissue grinding analysis of the experimental groups and the control groups were measured.Results:The bone-implant contact rates of the experimental groups were significantly higher than those of the control groups,and the trabecular spaces in the experimental groups were significantly lower than those in the control groups (P＜0.05).The average rotational torque values of the experimental groups were significantly higher than those of the control groups in the 4th and 8th week(P＜0.05).In the 4th week,the osseointegration rate of the implants in the experimental group was significantly higher than that in the control group,and the percentage of trabecular bone area of the implants increased significantly (P＜0.05).The histological results showed that:After loaded DCEF,the bone around the implants extended to the implants surface and formed a pseudopod-like structure.The experimental groups were more closely adherent to the implants surface than the control groups.There were a large number of new trabecularbone and bone-like matrix on the surface of the implants.The trabecular bone was connected with each other into a net-like structure.The implant-bone interface in the experimental groups had uniform new bone.In the control groups,new bone tissues were loose,bone tissues maturity and the degree of tightness of the implant-bone were less.Conclusion:DCEF can enhance the implant-bone density of SD rat tibia,promote osteointegration.