Risk factors affecting postoperative hemorrhage after tooth extraction in middle aged and elderly patients taking aspirin long-term

doi:10.3969/j.issn.1672-2973.2016.06.003

Abstract：Objective:To investigate and analyze the risk factors affecting postoperative hemorrhage after tooth extraction in middle aged and elderly patients taking aspirin long-term.Method:Middle aged and elderly patients taking aspirin long-term (120 cases) and without the use of antithrombotic drugs in recent 6 months (120 cases) were selected as the experimental group and the control group.The differences of hemorrhage rate after tooth extraction between two groups were analyzed from the gender,age,international normalized ratio (INR),number of platelets,the number of tooth extraction,tooth position,the complexity of surgery and operation time,respectively.Result:① The hemorrhage rate of the experimental group (13.33％) was significantly higher than that of the control group (3.33％) (P ＜0.05);② In each gender and age group,the hemorrhage rate of the experimental group was higher than that in the control group.However,only 75-80 years' old group had statistical significance (P ＜0.05);③ There was no significant difference in the hemorrhage rate of the experimental group and the control group in the INR and the platelet count groups;④ When more than 3 teeth were extracted,when the molar,complicated tooth or buried impacted tooth were extracted,and when operation time was between 5-10min,the hemorrhage rate of experimental group was significantly higher than that of the control group (P ＜ 0.05).The results of Logistic regression analysis showed that the number of tooth extraction,tooth position and the complexity of surgery had a significant relationship with the hemorrhage after tooth extraction (P ＜ 0.05).Conclusion:① Aspirin can increase the hemorrhage rate after tooth extraction in middle-aged and elderly patients taking it long-term,which is one of the risk factors for the hemorrhage after tooth extraction;② It is relatively safe for the patients without interrupting the taken of aspirin when having less than 4 simple teeth extraction with less trauma.