Characteristics in patients with sudden total deafness and their auditory prognosis
SHAN Changshuo
GAO Yun
WU Xiaonan
LI Danyang
LI Jin
ZHOU Rui
CHEN Guohui
WANG Hongyang
GUAN Jing
WANG Dayong
WANG Qiuju
Abstract：Objective To report post-treatment hearing in patients with unilateral sudden total deafness and factors affecting post-treatment hearing.Methods Patients with sudden total deafness(n=290)hospitalized from July 2008 to October 2022,aged 18～60 years and within 14 days of onset,were selected and grouped according to their post-treatment hearing,i.e.:complete recovery(CR),flat recovery(FR),high-frequency descending recovery(HFD),high-frequency ascending recovery(HFA)and No recovery(NR).Associations with age,sex,affected side,associated symptoms,predisposing factors,comorbidities,time of treatment onset,initial hearing threshold and laboratory test results were analyzed with the SPSS 26.0 software.Results In the 290 patients,post-treatment hearing was characterized as CR in 31(10.7%),FR in 69(23.8%),HFD in 157(54.1%),HFA in 1(0.3%)and NR in 32(11.0%),resulting in a total effective rate of 89.0%.Univariate analysis showed differences among the 289 patients whose post-treatment hearing was categorized as CR,FR,HFD or NR in vertigo,ear fullness,time of treatment onset,initial hearing threshold,activated partial thromboplastin time(APTT)and triglyceride(P<0.05).Pairwise comparison revealed differences in vertigo,time of treatment onset,initial hearing threshold and triglyceride between those with CR and FR(P<0.05);in vertigo,time of treatment onset,initial hearing threshold and APTT between those with CR and HFD(P<0.05);in vertigo,ear fullness,time of treatment onset and initial hearing threshold between those with CR and NR(P<0.05);in initial hearing threshold w between those with FR and NR(P<0.05);in ear fullness and APTT between those with FR and HFD(P<0.05);in ear fullness between those with HFD and NR(P<0.05);and not among other groups(P>0.05).Conclusions Although the rate of complete recovery is low in total sudden deafness(10.7%),total effective rate can be as high as 89.0%,with patients predominantly showing HFD recovery(54.1%).Post-treatment hearing recovery in patients with total sudden deafness is closely correlated with accompanying vertigo,ear fullness,initial hearing threshold,onset of treatment and coagulation dysfunction.
Keywords：sudden hearing losshearing curveprognosis
Publication Date：2025-12-20
Online Publishing Date：2025-12-11(First online date of this platform, not the publication date of the document)
Pages：6( 1019-1024 )