Characteristics of Cortical Auditory Evoked Potential P1-N1-P2 Waveforms in Miniature Pigs
YANG Chongling
TANG Fei
ZHONG Minxuan
GUO Weiwei
LÜ Ping
LIU Jun
Abstract：Objective To report a method for detection of cortical auditory evoked potential(CAEP)and characteristics of P1-N1-P2 waveforms in miniature pigs.Methods P1-N1-P2 waveforms were recorded in male miniature pigs with normal hearing(n=4)using tone bursts under anesthesia,including P1-N1-P2 latencies and amplitudes.Results P1-N1-P2 waves were detected in all 4(8-ears)animals(100%).The latency was 45.13±14.07 ms for P1,(96.00±10.72)ms for N1,and(135.13±13.95)ms for P2,while the amplitude was(2.21±1.04)μV for P1-N1,and(1.37±0.37)μV for N1-P2.Conclusion P1-N1-P2 waves reflect the auditory cortex function in miniature pigs and are similar to those in humans.Miniature pigs can be an animal model for studying auditory cortex function.
Keywords：miniature pigsauditory cortexcortical auditory evoked potentialP1-N1-P2latencyamplitude
Publication Date：2025-11-20
Online Publishing Date：2025-10-29(First online date of this platform, not the publication date of the document)
Pages：5( 953-957 )