Association between Clinical Symptoms and Vestibular Function in Meniere's Disease at Different Stages
ZHANG Xiaogang
LU Xiaohui
GONG Wentao
YU Jun
Abstract：Objective To investigate the association between clinical symptoms and vestibular function at different stages of Ménière's disease(MD).Methods Data from patients with MD(n=187)diagnosed at the Vertigo Specialty Clinic of Yantai Yeda Hospital between June 2020 and October 2022 were retrospectively analyzed.Based on hearing thresholds,MD was classified StageⅠ(n=18),Ⅱ(n=30),Ⅲ(n=97)or Ⅳ(n=42).Clinical data,symptoms and vestibular test results were reviewed and compared.Results Age and affected side showed significant differences for the four disease stages(P<0.05),together with significant differences in subjective hearing loss,photophobia,motion sickness,sleep disturbances,hypertension,hyperglycemia and hyperlipidemia(P<0.05),as well as in vHIT(gain+saccades)and vHIT(saccades)results(P<0.05).Conclusion The rate of abnormal video head impulse test(vHIT)is positively correlated with MD staging,and increases with disease progression.Saccade parameters may serve as important indicators in MD diagnosis.
Keywords：Ménière's diseasevestibular function testsvideo head impulse testsaccadesclinical characteristicsstaging
Publication Date：2025-11-20
Online Publishing Date：2025-10-29(First online date of this platform, not the publication date of the document)
Pages：5( 935-939 )