Progress Research on Cochlear Immune Microenvironment in Hearing Loss of Different Etiologies
XIA Miao
WANG Yanfe
LI Bingqian
ZHAO Hongchun
SUI Zhimiao
WANG Lan
CHEN Jun
Abstract：Hearing loss is a global issue that affects the lives of billions of people.Sensorineural hearing loss can be categorized into three main types based on etiology:i.e.noise induced,age-related and genetic hearing loss.Cochlear immune microenvironment(CIM)is a crucial regulator of cochlear homeostasis.Macrophages,as the primary executors in the CIM,play a pivotal role in the development and progression of hearing loss.This article discusses the roles of CIM as represented by cochlear macrophages in hearing loss by various etiologies.A thorough understanding of the regulatory mechanisms by macrophages can contribute to the development of novel preventive and therapeutic strategies to combat hearing loss.
Keywords：noise-induce hearing lossage-related hearing losshereditary hearing lossmacrophageimmunity
Publication Date：2025-08-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 705-709 )