A Case of Secondary Acquired Cholesteatoma
Abstract：Secondary acquired cholesteatoma (SAC) is a special type of middle ear cholesteatoma that occurs secondary to chronic otitis media with tympanic membrane perforation. The classification of this disease highlights its etiological factors, while its biological characteristics are essentially no different from other types of cholesteatoma. Like the most common type of cholesteatoma, SAC presents with persistent or intermittent otorrhea, which may be purulent with an odor, and is often accompanied by tinnitus, ear pain, varying degrees of hearing loss, vertigo, and in advanced stages, can lead to serious intracranial and extracranial complications. On physical examination, it is distinguished from the typical retraction pocket perforation of middle ear cholesteatoma by the presence of a central perforation of the tympanic membrane. Due to the rarity of this type of middle ear cholesteatoma and the early use of effective antibiotics leading to atypical clinical manifestations, diagnosis can be challenging. In this article, we report a case of SAC presenting during the quiescent phase of chronic suppurative otitis media and discuss ways to reduce misdiagnosis and missed diagnosis. This study was approved by the Ethics Committee of the 900th Hospital of the Joint Logistics Support Force (No. 2024-038). The patient and family provided informed consent for the study.
Keywords：secondary acquired cholesteatomathe epithelial migration theoryperforation of the tympanic membraneotorrhea
Publication Date：2025-07-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 619-621 )