Correlation Between Objective Auditory Response Thresholds and Pure-Tone Thresholds in Age-Related Hearing Loss
LIN Shaolian
CHEN Zhifeng
SHU Bo
HU Jie
LIN Dingding
CHI Tonghan
LIN Chang
Abstract：Objective To examine the correlation between thresholds of cortical auditory evoked potentials(cAEPs),40 Hz auditory event-related potentials(40 Hz-AERPs)and multiple-frequency auditory steady-state responses(ASSRs),and pure-tone audiometry(PTA)thresholds in patients with age-related hearing loss(ARHL).Methods A total of 122 patients(67 males and 55 females)with age-related hearing loss admitted to the Department of Otolaryngology Head and Neck Surgery,First Affiliated Hospital of Fujian Medical University,from January to December 2023 were selected.Correlations between PTA thresholds and thresholds of cAEPs,40 Hz-AERPs(0.5 and 1 kHz)and ASSRs(0.5,1,2 and 4 kHz)were analyzed.Results Except for the severe group ARHL,cAEP thresholds were correlated with PTA thresholds at 2 and 4 kHz(P<0.05).The difference(8.08±4.88～15.13±9.76 dB)between 40 Hz-AERP thresholds and PTA thresholds at 0.5 kHz was smaller than at 1 kHz.Excluding profound loss,at 1 kHz,40 Hz-AERP thresholds were correlated with PTA thresholds at 0.5 and 1 kHz(P<0.05).The difference between ASSR and PTA thresholds was greater at 0.5 kHz than at 1,2 and 4 kHz.In those with mild hearing loss,the greatest disparity between ASSR and PTA threshold at 0.5 kHz was 16.13±12.32 dB.Except for profound loss at 2 kHz,ASSR and PTA thresholds showed significant differences among different levels of hearing loss and correlation with each other(P<0.05).Conclusion Combined 40 Hz-AERPs and ASSRs can predict PTA thresholds at 0.5 and 1.0 kHz.and combined cAEPs and ASSRs can predict PTA thresholds at 2.0 and 4.0 kHz.Combining 40 Hz-AERPs,cAEPs,ASSRs and PTA can provide more accurate assessment of the degree of hearing loss in patients with ARHL.
Keywords：age-related hearing lossauditory brainstem responses40 Hz auditory event-related potentialsmultiple-frequency steady-state auditory evoked potentialspure-tone audiometry
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 955-960 )