Correlation Between Vestibular Aqueduct Morphology and Occurrence of Ménière's Disease

MAO Qiuyue; YANG Tao; DENG Kai; PENG Anquan; ZOU Shuguang; ZHANG Yiling; ZHANG Kangjia; WANG Qin

doi:10.3969/j.issn.1672-2922.2024.06.005

Abstract：Objective To investigate the correlation between the occurrence of Ménière's disease(MD)and the morphology of the vestibular aqueduct(VA).Methods Data from patients with Meniere's disease(n=120,64 females and 56 males,aged 53.18±11.81 years)diagnosed in the Department of Otorhinolaryngology Head and Neck Surgery,the Second Xiangya Hospital of Central South University,from May 2,2018 to December 15,2021 were retrospectively analyzed,after excluding those with incomplete imaging data or other outer,middle and inner ear lesions.Patients with acoustic neuroma(n=98,56 females and 42 males,aged 49.63±11.63 years)were included as the control group.Temporal bone scans were acquired using Siemens dual-source force CT.The vestibular aqueduct was graded on the plane of the semicircular canal.Levels 0 and 1 were classified as displayable,and level 2 non-displayable.The Graphpad prism 9.3.1 and SPSS 25 software was used for data analysis.Results The vestibular aqueduct was graded as 0 in 12 patients,1 in 62 patients and 2 in 46 patients.Similarly,the vestibular aqueduct was graded as 0 in 51 of the control patients,1 in 39 and 2 in 8(P=0.32).There was a significant difference between the displayable and non-displayable types in both the MD patients and control patients(P<0.01).There was no correlation between display types and hearing change(P>0.05),although the degree of hearing loss in MD patient was positively correlated with age(P=0.005).Conclusion Morphology of the vestibular aqueduct shows significant differences between MD patients and non-MD patients.Non-displayable vestibular aqueducts on temporal bone CT scans may be related to pathogenesis of MD.VA levels have no significant effect on hearing changes in MD.