Advances in Epigenetic Research on Age-related Hearing Loss
CHEN Rongjun
HUANG Xinzhao
FU Wen
PENG Hua
Abstract：There will be a series of aging phenomena in the human body with age.Clinically,age-related hearing loss(ARHL)is a progressive and symmetrical bilateral neuro-sensory hearing loss in the elderly.The pathogenesis of ARHL is complex.Genetic susceptibility is one of the important factors of ARHL.Epigenetics,including DNA methyla-tion,non-coding RNA regulation and histone modification,is closely related to the occurrence and progression of AR-HL.This paper reviews the recent advances in epigenetics research on ARHL,in order to promote prevention and treat-ment of ARHL.
Keywords：age-related hearing lossepigeneticsDNA methylationnoncoding RNAhistone modification
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 307-310 )