Effects of Cochlear Implantation in Patients with Waardenburg Syndrome:A Meta Analysis
QIN Feng
GUO Siquan
MA Jing
LU Xiaoyu
Abstract：Objective To evaluate the value of cochlear implantation as a treatment for WS by comparing hearing and speech recovery after cochlear implantation between Waardenburg syndrome(WS)and non Waardenburg syndrome patients.Methods The literatures on WS cochlear implantation published in China and abroad were retrieved from the PubMed,Cochrane Library,CNKI,VIP medicine and Wanfang databases,and clinical data of studies meeting the inclu-sion criteria were analyzed using the Revman5.41 software.Results A total of 8 articles were included in this study,in-cluding 108 patients with WS and 785 control groups.Meta analysis showed that the scores of categories of audit perfor-mance(CAP)in the WS group and the control group(48 cases in the WS group and 620 Cases in the control group)(MD=-0.10,95％CI-0.38～0.17,P=0.46)Speech intelligibility rating(SIR)score(48 cases in WS group and 620 Cases in control group)(MD=-0.23,95％CI-0.68～0.22,P=0.31),,parents'evaluation of aural/oral performance of children,peach[telephone score(37 cases in WS group and 53 cases in control group)(MD=0.13,95％ CI-0.48～0.74,P=0.68),quiet score(37 cases in WS group and 53 cases in control group control group(53 cases)(MD=-0.01,95％CI-0.10～0.09,P=0.91),noise score(37 cases in WS group and 53 cases in control group)(MD=-0.01,95％ CI-0.11～0.10,P=0.88)]there was no significant difference.Conclusion The hearing and speech recovery of WS patients after cochlear implantation was basically the same as that of non WS patients.
Keywords：waardenburg syndromecochlear ImplantionMeta analysis
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 785-790 )