Correlation between Serum Apolipoprotein Level and Hearing Prognosis in Patients with Sudden Sensorineural Hearing Loss
ZOU Xinbo
TANG Xuxia
LV Zhenyi
HE Xiao
Abstract：Objective To investigate the influence of serum apolipoprotein level on hearing prognosis in patients with sudden sensorineural hearing loss.Methods Clinical data from 210 patients with sudden sensorineural hearing loss were retrospectively analyzed by t test,analysis of variance,Chi-square test and multivariate logistic regression,in-cluding gender,hypertension,diabetes,pattern of audiogram,ApoA,ApoB,ApoA/ApoB severity of hearing loss and treatment outcomes,with a focus on the association between levels of ApoA,ApoB,ApoA/ApoB and clinical character-istics as well as prognosis on hearing.Results Levels of ApoA and ApoA/ApoB were different between male and fe-male patients(P=0.009 and P=0.006,respectively),and levels of ApoA were different between patients with and with-out hypertension(P=0.042).Levels of ApoA decreased in patients with low frequency,high frequency,flat or total deaf-ness,while the level of ApoB and ApoA/ApoB increased in the same order.Hypertension was correlated with worse prognosis.Conclusion Serum levels of ApoA,ApoB and ApoA/ApoB may not be associated with the prognosis in sud-den deafness,while hypertension appears to be a risk factor for unfavorable prognosis.
Keywords：Sudden sensorineural hearing lossApoAApoBApoA/ApoB
Publication Date：2023-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 632-638 )