Long-Term Efficacy Comparison between Semicircular Canal Occlusion and Endo-lymphatic Sac Decompression in Intractable Meniere's Disease
WANG Huibing
SUN Hanjun
LI Jian
Sun Qing
CHEN Yuanxing
GAO Yun
DAI Jing
SHAN Xizheng
Abstract：Objective To compare long-term efficacy of semicircular canal occlusion (SCO) and endolymphatic sac decompression (ESD) in intractable advanced Meniere's disease (MD). Methods A total of 129 cases of intractable MD were analyzed retrospectively, including 76 treated with ESD and 53 with SCO. The frequency and severity of vertigo attacks, hearing changes, tinnitus and aural fullness were compared between the two groups. Postoperative follow-up period ranged from 24 to 50 months. Results Vertigo attacks were effectively controlled in 60 patients treated by ESD (78.95%) and in 52 patients treated by SCO (98.11%) with significantly decreased vertigo attacks (P<0.05), more so in those treated by SCO than in those by ESD（X2=10.025, P<0.01）. The severity of vertigo was decreased after either ESD (U=8.265, P<0.01) or SCO (U=8.178, P<0.01) operation, more so after the latter (U=5.163, P<0.01). Residual hearing was preserved in 86.84% of cases after ESD and in 83.02% of cases after SCO, respectively（X2=0.363, P>0.05）. The rate of tinnitus improvement was 55.26% after ESD and 49.06% after SCO（X2=0.483, P>0.05）. Relief of aural fullness after operation was reported in both groups (U=2.495, 2.305> 1.96, P<0.05), 43.42% after ESD and 52.83% after SCO（X2=1.109 ,P>0.05）. Conclusion Both SCO and ESD are effective in controlling the frequency and severity of vertigo attacks in intractable MD, with SCO seemingly better in vertigo improvement. Postoperative hearing change is similar after ESD and SCO. Tinnitus and aural fullness can be similarly improved by both ESD and SCO.
Keywords：Meniere's DiseaseSurgical TreatmentEndolymphatic Sac DecompressionSemicircular Canal OcclusionEfficacy
Publication Date：2021-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 546-550 )