Evaluation of Central Auditory Speech Recognition Function by Mismatch Negativity(MMN)

LIU Haoqiang; ZHAO Lidong

doi:10.3969/j.issn.1672-2922.2018.02.019

Abstract：Speech recognition functions are often affected by various neurological factors,brain diseases and oth-er conditions.Event-related potential(ERP)is a brain response with phase-locked time specific events.It is a window for studying cerebral cognition and auditory information recognition,reflecting changes in electrophysiological activi-ties of the brain during cognitive processes.At present,components such as slow reaction P1-N1-P2,Mismatch Negativ-ity(MMN),N2b-P3b and N400 can be extracted from ERP.MMN is an endogenous ERP component that reflects the brain's automatic processing of information,with the fact that it does not require the patient to take the initiative to par-ticipate,can be measured in an unconscious situation and is gaining increasingly wide use in the clinic.MMN has been used as tools for studying obstacles in areas such as auditory recognition.In many diseases conditions,compared with the normal control,MMN displays substantially reduced amplitudes and/or delayed latencies.While this general finding suggests that MMN cannot be used as a specific indicator of any particular disease,it may still help understand telltale signs of certain diseases involving central auditory speech disorders and may serve as a potential indicator of the risk of these diseases.