Correlations Between Middle Ear Cholesterol Granuloma and Dyslipidemia
ZHANG Kun
ZHANG Endong
QU Peng
FU Tao
WANG Zhiyuan
CHEN Xiaoqing
Abstract：Objective To study the relationship between middle ear cholesterol granuloma and dyslipidemia by analyzing characteristics of lipid metabolism in patients with middle ear cholesterol granuloma.Methods Serum triglyc-eride (TG),total cholesterol (TC),low density lipoprotein cholesterol (LDL),high density lipoprotein cholesterol (HDL),apolipoprotein A1(APOA1)and apolipoprotein B(APOB)contents in 57 cases of middle ear cholesterol granu-loma were retrospectively analyze and compared to 57 age and gender matched cases of chronic otitis media without cholesterol granuloma (based on pathological and imaging diagnoses).Results TC,LDL,APOA1,LDL/APOA1,and APOB/APOA1 levels in cases of middle ear cholesterol granuloma were higher than in cases without cholesterol granu-loma(P<0.05),but TG,HDL,APOB and HDL/APOB levels showed no difference between the two groups(P>0.05).Logistic multiple factors analysis showed that TC,LDL were risk factors for middle ear cholesterol granuloma.Conclu-sion Patients with middle ear cholesterol granuloma show higher lipid levels than patients without middle ear cholester-ol granuloma,and TC,LDL,APOA1,LDL/APOA1 and APOB/APOA1 levels show correlation with the onset of mid-dle ear cholesterol granuloma.
Keywords：Cholesterol GranulomaChronic Otitis MediaBlood Lipid Metabolism
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 705-708 )