Pathogenesis and audiologic performances in hidden hearing loss
LI Guoqing
LV Ping
WANG Qiuju
Abstract：Hidden hearing loss is a suprathreshold auditory perceptual deficits which only manifests as deteriorat-ing speech recognition in noise, and is usually not identified by routine clinical hearing threshold tests and thus often un-detected. This article describes the pathogenesis and auditory performance in hidden hearing loss, focusing on impair-ment of three important parts of the cochlear afferent pathway, i.e. synapses between outer and inner hair cells and spiral ganglion cells and postsynaptic afferent pathways;cochlear glutamate-glutamine cycles;and the cochlear efferent sys-tem, including lateral olivocochlear bundles and cochlear afferent synaptic complex formation of the third synaptic and medial olivocochlear bundles, in order to provide an evidence based basis for early diagnosis of hidden hearing loss, and theoretical and experimental bases for early intervention in hidden hearing loss.
Keywords：Hidden hearing lossglutamic acid-glutamine cycleCochlear afferent synaptic complex
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 185-190 )