Research progress of MicroRNA in the pathogenesis of cholesteatoma
Baheti jiang.tuokejigete
Ayheng qukuerhan
Abstract：MicroRNA which has variety of biological functions in cells is a small RNA molecule in the organism, par-ticipates in transcriptional regulation, energy metabolism, growth, reproduction and so on. MicroRNAs are important mole-cules in cell gene regulation in body, and exercise a variety of biological function. In recent years, a large number of molecu-lar biology researches in pathogenesis of cholesteatoma of middle ear , have made a new progress of which miRNAs study and opened a new field.MiR-21 may be related with the occurrence and development of cholesteatoma of middle ear, and has played a potential role in cholesteatoma of middle ear in growing and diffusing. This paper reviewed the researching progress of the miR-21 and cellular signaling pathways and their interaction in occurrence mechanism and development of cholesteatoma of middle ear .
Keywords：Cholesteatoma of middle earMicroRNAsPathogenesis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 304-307 )