Ocular vestibular evoked myogenic potentials in patients with Meniere's disease
RAO Rendong
SUN Qing
PENG Xin
JI Li
ZHANG Yongbin
WANG Ning
SHAN Xizheng
Abstract：Objectives To report ocular vestibular evoked myogenic potential (oVEMP) results in a group of patients with Meniere's disease. Methods We enrolled 66 patients with Meniere's disease as the observation group and 27 (54 ears) age-and gender-matched normal subjects as the control group. Both patients and normal subjects underwent conventional oVEMP tests in bilateral ears. The results of the affected ears were compared with the contralateral ears and with the normal controls. Results oVEMPs were elicited in 30 affected ears (41.7%), 33 contralateral ears (55.0%) and all normal ears (100.0%). Difference in response rate was not found between the affected ears and the contralateral ears (P>0.05 ), but be-tween both affected ears and contralateral ears in patients and the normal controls (P<0.05). There were differences in the amplitude and asymmetry ratio among the affected ears, contralateral ears and control ears (P<0.05), but not in the latency. Overall, in patients with Meniere's disease, the rate of successful oVEMPs induction decreased as hearing grades worsened. Conclusion The rate of oVEMP responses in patients with Meniere’s disease (in both the affected and contralateral ears, but especially in the affected ear) is significantly lower than in normal subjects, suggesting damage to utricular functions in these patients. oVEMP examination can be used to evaluate utricular functions in Meniere’s disease, and guide diagnosis and treatment.
Keywords：Meniere's diseaseocular vestibular evoked myogenic potentialutricular functionvestibule
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 181-185 )