Excavation and application of the Rongchang Pig hereditary pedigree connected to hearing defects
CHEN Wei
CHEN Lei
YANG Shiming
Abstract：As a different class of animal model from mice, pig is being highly valued in areas including comparative biology, developmental biology, medical genetics and animal husbandry. Our representation describes a variation of the unique Rongchang pig strain-Rongchang hereditary pedigree connected to hearing defects . The mutation sites, pathology and pathogenesis are very similar to those in human Waardenburg syndrome type 2A. Application of this pedigree, in the field of hearing research, benefits the study on treatment of neurosensory hearing loss with stem cell transplantation, early genetic intervention, auditory device implantation, etc. Moreover, it provides an ideal model of large mammals with respect to hearing medicine sciences.
Keywords：Rongchang piganimal modelhearing medicine science
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 10-14 )