Abnormal Purine Metabolism and Hearing Loss
Wang Xin
Zhang Pu
Zhang Xun
Abstract：[Abstact]Purine, one chemical constituent existing in the human body, participates in the production of a variety of important substances including nucleic acids and ATP. Abnormal metabolism of purine leads to a series of diseases (e.g., gout, autoimmune diseases, blood diseases, kidney diseases, etc). However, reports on the relationship between purine and hearing loss as hereditary deafness are rare. In this paper, we will summa-rize study evidence on the association between abnormal purine metabolism and hearing loss, and discuss the pathogenesis of non-hereditary deafness resulting from abnormal purine metabolism.
Keywords：PurineMetabolic abnormalitiesHereditary deafnessNon-hereditary deafness
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 754-756 )