Effects of radiotherapy on bone conduction hearing thresholds in early stage nasopharyngeal carcinoma
GUO Mingkun
XUE Ming
ZHANG Ke
Abstract：Objective To investigate radiation-induced sensorineural hearing loss in early nasopharyn-geal carcinoma. Methods Clinical data of patients with nasopharyngeal carcinoma treated by the authors from February 2006 to March 2012 were collected. Conventional pure tone audiometry test was conducted. DPOAE and bone conduction thresholds were recorded for frequencies of 0.5, 1, 2 and 4 kHz to compare hear-ing before and at 1.5 and 2 years after radiotherapy. Thresholds were examined separately for each frequency. Results Bone conduction thresholds before radiotherapy were lower than those at 1.5 and 2 years after radio-therapy. The differences were statistically significant for all frequencies (P<0.05). At 1.5 and 2 years after ra-diotherapy, DPOAE failing rate increased (P<0.05). Conclusion This study shows that the bone conduction threshold increases significantly in patients with early stage nasopharyngeal carcinoma treated with radiothera-py. All measures of prevention and treatment should be considered as early as possible in patients with naso-pharyngeal carcinoma who are receiving radiotherapy to prevent advance of sensorineural hearing loss.
Keywords：nasopharyngeal carcinomaradiotherapybone conductionauditorythresholdhearing loss-thresholdhearing loss
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 522-524 )