Factors affecting 3T MRI in Detecting Endolymphatic Hydrops in Meniere’s Disease
YANG Feng
LIU Yang
Wang Qingjun
ZHAO Danheng
ZHAO Pengju
SUN Jianjun
SONG Rendong
Abstract：Objective The aim of this study was to discuss feasibility and reliability of 3T MRI in detect-ing endolymphatic hydrops (EH) in Meniere’s disease (MD). Another aim was to assess factors that might af-fect study results. Methods Forty-three patients with unilateral clinically confirmed MD were evaluated with inner ear MRI. MRI imaging was completed 24 h after intratympanic administration of gadolinium chelate. The sequence of MRI was three-dimensional fast spin-echo T1-weighted imaging (3D-FSE-T1WI). A 3-point scoring system was used in the assessment of EH. Positive results were analyzed. Results MRI signs of vestibu-lar EH were positive in 35 of the 43 patients (81.40%), negative in 4 patients (9.30%) and inclonclusive in 4 pa-tients (9.30%). MRI signs of cochlear EH were positive in 36 of the 43 patients (83.72%), negative in 3 pa-tients (6.98%) and inconclusive in 4 patients (9.30%). Conclusion After intratympanic injection of gadolinium, inner ear MRI is a practical and reliable method for detecting EH in MD. The main influencing factors include obstruction of contrast agent diffusing into the inner ear, techniques of intratympanic administration, MRI de-tection sequences and physician judgment factors.
Keywords：Meniere's diseaseendolymphatic hydropsMRIgadolinium
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 493-496 )