The Progress of AP-2 Protein Regulating Clathrin Mediated Endocytosis
GU Xiang
YUAN Wei
Abstract：Neural transmission is dependent on the release of neurotransmitter. Synaptic vesicle recycling is the basis of neurotransmitter release. Clathrin-mediated endocytosis plays a key role in the synaptic vesicle reformation. AP-2 is a key protein in different periods of endocytosis, which can bind other protein molecules to regulate the vesicle recycling from the as?pects of structure and dynamics. This review summarizes the molecular structure and characteristic of AP-2 and discusses the relationship between clathrin-mediated endocytosis and hearing.
Keywords：ClathrinAdaptinEndocytosisSsynaptic vesicleInner hair cell
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 349-354 )