A Study of a Projection From the Dorsal Raphe Nucleus to the Inner Ear by Antrograde Label Tracing Technique
YANG Mi
LIU Jiajia
LI Shisheng
WANG Shuang
LIU Bingbing
YANG Xinming
Abstract：Objective We have proved the efferent nerve connections between DRN and inner ear in early research. The aim of this study is to investigate the way of projection from the dorsal raphe nucleus(DRN) to the inner ear. Methods Highly sensitive Biotinylated Dextrain Amine(BDA) was injected into DRN of cat,and the cochlea was taken after survival peri?od of 10 days. BDA positive was observed in the spread piece of the inner ear hair cells. Results 1. It was found that rare hair cells labeled with BDA which is dark brown after immunohistochemical staining. These BDA-positive cells irregular distribut?ed mainly in the first row and second row of outer hair cells, and haven’t see the staining in the inner hair cells. 2. It was found that several fibers companied with BDA-positive cells from modiolus to the bottom of the outer hair cell. Conclusion The pres?ent results suggest that a fibers connection between DRN and inner ear hair cells may exist. The link is mainly exists in the first row and second row of outer hair cells.
Keywords：Dorsal raphe nucleus(DRN)Inner earBiotinylated Dextrain Amine(BDA)
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 332-334 )