The Follow-up Study on Audiological Characteristics of Auditory Neuropathy Spectrum Disorder

XIE Linyi; LAN Lan; WANG Dayong; YU Lan; SHI Wei; ZHANG Qiujing; HAN Bing; WANG Hongyang; GUAN Jing; LIU Qiong; WANG Qiuju

doi:10.3969/j.issn.1672-2922.2015.02.009

Abstract：Objective To analyse the audiological characteristics of patients with auditory neuropathy spectrum disorder (ANSD) for gaining a better understanding of the audiological characteristics prognosis of ANSD patients. As well as to make a scheme for patients’further consulation, facilitating the patients’further consulation. Methods 22 patients (40ears) with ANSD were enrolled, all of whom had received further consulation within 17 years after the first consulation. Pure tone test, speech-discrimination score test (SDS), distortion product otoacoustic emission (DPOAE), acoustic immitance testingand au?ditory brainstem response (ABR) were performed on these patients. Results The differences between the first consulation and the further consulation are as follows:①There were no significant changes in pure tone average(P>0.05).②The SDS of the patients who came back for further consulation in 3 years differ from the ones who came back in 7 years(P<0.05).③Most patients had almost all the sensitive DPOAE in the first consulation, while they had worse results in the low frecequeces in the further consulation. The whole frequences of the DPOAE became worse in the patients who came back for further consula?tion in 3 years .④The acoustic reflex (AR) results decrease from 20%to 5%.⑤There were no significant changes in the ABR. Conclusion ①With the development of the disease, we can see the SDS, the DPOAE results and the AR results be?came worse. As a result, a part of the patients with ANSD would perform like the ones with sensorineural hearing loss (SNHL). So we must pay attention to those patients who complain that they can hear the sound without understanding what others are talking about.②It is necessary to improve the scheme of patients’further consultation, easing the follow-up study and fur?ther understanding the clinical prognosis of ANSD.