Whole Exome Sequencing and Its Application in Genetic Hearing Loss Research
JIANG Haiou
QUAN Qingli
HU Xiangshang
WANG Yiwang
Abstract：In recent years, the rapid development of whole exome sequencing (WES) has brought new opportunities for the study of genetic diseases. It has been attached importance and applied to many types of genetic diseases, especially heredi?tary hearing loss. WES uses target capture methods to enrich sequences of coding regions of genes throughout the genome, fol?lowed by high-throughput sequencing of the captured fragments. This article mainly reviews the technology of whole exome sequencing as well as its recent applications to the study of hereditary hearing loss and relevant achievements.
Keywords：Whole exome sequencingGenetic hearing lossCausative gene
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 179-182 )