Clinical Features of Langerhans Cell Histiocytosis of Temporal Bone
LI Xiaohong
HAN Weiju
Abstract：Objective Temporal bone Langerhans Cell Histiocytosis (LCH) is mainly characterized by otorrhea, mas?toid mass, granuloma in the middle ear and external auditory canal, and hearing loss,while facial paralysis is rare. This study is aimed at analyzing clinical and prognostic features of temporal bone LCH. Methods Clinical data from 16 cases of LCH of the temporal bone treated from July 2009 to July 2014 at the Chinese PLA General Hospital were reviewed, including fol?lowing ups clinical presentation, ,The 2009 International Histocyte Society guidelines for diagnosis, clinical classification and outcome evaluation were adopted in the analysis. Correlation between age and clinical classifications and prognosis was also analyzed. Results Among the 16 patients, 10 were children (≤4 years old) and 6 were adults (24-68 years old). Multiple system involvement was seen in 4 of the 16 patients, and the rest patients showed only single system involvement. While age was not correlated to treatment outcomes, clinical classification appeared to be correlated to the prognosis. Conclusion The number of organ affected by LCH may be a good prognosis indicator in these patients.
Keywords：Temproal boneLangerhans histiocytosisDiagnosisSurgeryPrognosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 101-105 )