Efficacy of Postauricular Methylprednisolone Injection for Refractory Sudden Hearing Loss
JING Yuanyuan
YU Lisheng
MA Xin
SHAO Senyao
ZHENG Hongwei
Abstract：Objective To assess the efficacy of postauricular injection of methylprednisolone in treating refractory sud-den hearing loss. Methods Forty five cases of sudden hearing loss that failed systematic glucocorticoids therapy were includ-ed in this study and divided into two groups. The Control group (n=23) was given only conventional treatment. The postauricu-lar injection group (n=22) received 3 doses of postauricular injection of methylprednisolone at 20 mg qd. in addition to con-ventional treatments. Results At 2 weeks after treatment, the rates of complete recovery and significant improvement were 50%(11/22) and 22.7%(5/22) in the postauricular injection group, and 30.4%(7/23)and 0 in the control group, respectively. Pure tone audiometry at all frequencies improved by 20.01±14.11 dB on average in the postauricular group, and 10.47±8.53 dB in the control group. The difference was statistically significant (P=0.0087). The PTA at 250 Hz and 500 Hz improved by 24.09±16.95 dB and 25.23±18.29 dB in the postauricular injection group, and 10.43±9.87 dB and 11.52±9.46 dB in the con-trol group. The difference again was statistically significant (P=0.0018, P=0.0027). Conclusion Postauricular methylprednis-olone injection is an effective therapy for refractory sudden hearing loss, especially for low-frequency involvement.
Keywords：Postauricular injectionSudden hearing lossMethylprednisolone
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 452-454 )