Resting-state Functional MR Study in Unilateral Sensorineural Hearing Loss by Amplitude of Low-frequency Fluctuation
FENG Yuan
CHEN Yuchen
LIU Bin
ZHANG Lingling
YANG Ming
HUANG Zhichun
Abstract：Objective To investigate the change of amplitude of low-frequency fluctuation (ALFF) in resting-state func-tional magnetic resonance imaging (fMRI) in patients with long-term right side sensorineural hearing loss (SNHL). Methods Resting-state fMRI data were collected from 20 patients with long-term right side sensorineural hearing loss and 20 normal subjects. Using these data, the ALFF were mapped following post-BOLD processing and compared between the SNHL and nor-mal groups. Results In the SNHL group, the ALFF showed a significant increase in bilateral superior and middle temporal gy-ri, insular lobes, uncinate gyri, right parahippocampal gyri and anterior lobe of cerebellum, and a decrease in the posterior part of right middle temporal gyrus. Conclusion The activation changes in relevant brain regions of patients with right side SNHL indicate the potential mechanisms of the brain function remodeling.
Keywords：Magnetic resonance imagingAuditory cortexSensorineural hearing loss
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 224-227 )