Meta-analysis of the clinical efficacy of treatment of sudden deafness using hyperbaric oxygen combined with drug in China
KU Wei
LIU Yehai
WU Jing
WANG Qiang
TONG Busheng
DUAN Maoli
Abstract：Objective To evaluate the clinical efficacy of treatment of sudden deafness using hyperbaric oxygen com-bined with drug in recent years. Methods We searched nearly five years Chinese academic journals, Chinese digital library, VIP Information Resource System, Superstar Digital Library, Chinese Biomedical Literature Database, Wanfang database about hyperbaric oxygen therapy combined drug therapy of sudden deafness randomized controlled studies met the inclusion criteria for the evaluation of methodological literature from 2008 to 2012 , and RevMan5.1 software and the quality standards Meta-analysis of randomized controlled studies were included. Result 20 randomized controlled studies were analyzed, a to-tal of 2554 cases, of which 1,347 cases received hyperbaric oxygen therapy combined with drug treatment as treatment group, in contrast 1,207 cases received drug therapy alone was the control group. We found that the treatment group had a signifi-cant clinical effect than contrast group (P<0. 00001), and in addition ,the early use of hyperbaric oxygen therapy had better effect than the patients with hyperbaric oxygen of treatment at late stage (P<0. 00001). Conclusion The application of hyper-baric oxygen therapy combined with drug show better than drug therapy alone was, and the introduction of hyperbaric oxygen therapy,at earlier stage shows better results.
Keywords：Hyperbaric oxygenationsudden hearing lossClinical effect
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 93-98 )