Clinical Application Status of Xuanshen(Scrophulariae Radix)and Its Chemical Components
JIE Shanshan
CHEN Bing
YU Zheng
MA Yaluan
Abstract：Xuanshen(Scrophulariae Radix)has a medicinal history of more than 2000 years in China,with the effects of clearing heat and cooling blood,nourishing Yin and reducing fire,detoxifying and dispersing nodules.This study utilized the academic platform of China National Knowledge Infrastructure(CNKI)to collect a total of 4175 articles related to Xuanshen published from 1956 to 2024.It was found that since 2004,the number of published papers has significantly increased.These literatures primarily focus on research in the fields of traditional Chinese medicine and pharmacology(74.92%of the total number of papers),with a small proportion(3.11%of the total number of papers)dedicated to clinical application research.The clinical application of Xuanshen is mostly in combination with formula.Xuanshen single herb can also be used to treat wind heat headache,cold,and Sjogren's syndrome.In recent years,with the research and excavation of pharmacological activities,it has been found that Xuanshen and its chemical components have multiple pharmacological effects,which can improve have potential effects and therapeutic value on inflammatory diseases such as gingivitis,tonsillitis,acute lymphadenitis,endocrine and metabolic diseases such as hyperthyroidism,diabetes,ischemic injuries such as cerebral ischemia-reperfusion and myocardial infarction,as well as tumors and other diseases.This study reviews existing literature,with a focus on the research of Xuanshen and its chemical components in the clinical application status,providing reference for expanding the clinical application scope of Xuanshen,and provide reference for related research.
Keywords：Xuanshen(Scrophulariae Radix)Chemical componentsClinical application status
Publication Date：2026-03-28
Online Publishing Date：2026-03-31(First online date of this platform, not the publication date of the document)
Pages：6( 675-680 )